Kevin Nee Profile Page
Kevin Nee


B.S. in Molecular, Cell, and Developmental Biology with a minor in Biomedical Research
After graduating from UCLA, I joined the Amander Clark lab to continue the research that I began as an undergraduate. I spent two years contributing to research that has lead to 5 publications. I am fortunate to join the MSTP program at UCI. Currently I am interested in the genetic regulation of pluripotency in tumor initiating cells.


Stem Cell Biology
PGC Reversion to Pluripotency Involves Erasure of DNA Methylation from Imprinting Control Centers followed by Locus-Specific Re-methylation.
Oliveros-Etter M, Li Z, Nee K, Hosohama L, Hargan-Calvopina J, Lee SA, Joti P, Yu J, Clark AT.
Stem Cell Reports. 2015 Sep 8;5(3):337-49. doi: 10.1016/j.stemcr.2015.07.006. Epub 2015 Aug 13.
PMID: 26278040

In vivo targeting of de novo DNA methylation by histone modifications in yeast and mouse.
Morselli M, Pastor WA, Montanini B, Nee K, Ferrari R, Fu K, Bonora G, Rubbi L, Clark AT, Ottonello S, Jacobsen SE, Pellegrini M.
Elife. 2015 Apr 7;4:e06205. doi: 10.7554/eLife.06205.
PMID: 25848745

The Aorta-Gonad-Mesonephros Organ Culture Recapitulates 5hmC Reorganization and Replication-Dependent and Independent Loss of DNA Methylation in the Germline.
Calvopina JH, Cook H, Vincent JJ, Nee K, Clark AT.
Stem Cells Dev. 2015 Jul 1;24(13):1536-45. doi: 10.1089/scd.2014.0410. Epub 2015 Apr 13.

The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice.
Li Z, Yu J, Hosohama L, Nee K, Gkountela S, Chaudhari S, Cass AA, Xiao X, Clark AT.
EMBO J. 2015 Mar 12;34(6):748-58. doi: 10.15252/embj.201489319. Epub 2014 Dec 17.
PMID: 25519955

MORC1 represses transposable elements in the mouse male germline.
Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE.
Nat Commun. 2014 Dec

Stage-specific roles for tet1 and tet2 in DNA demethylation in primordial germ cells.
Vincent JJ, Huang Y, Chen PY, Feng S, Calvopiña JH, Nee K, Lee SA, Le T, Yoon AJ, Faull K, Fan G, Rao A, Jacobsen SE, Pellegrini M, Clark AT.
Cell Stem Cell. 2013 Apr 4;12(4):470-8. doi: 10.1016/j.stem.2013.01.016. Epub 2013 Feb 14.
PMID: 23415914

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