Interaction of excitotoxic and oxidative mechanisms in selective motor neuron injury; a hypothesis of ALS pathogenesis
Postgraduate Training
Preliminary Medicine, Dartmouth
Last Known Position
Resident in Radiation Oncology, Washington University St. Louis
Website
Research Interests
PUBLICATIONS
Rao, SD; Yin, HZ; Weiss, JH., Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. Journal of Neuroscience(2003), Apr 1;23(7):2627-33.
Ketterer, K; Rao, S; Friess, H; Weiss, J; Buechler, M; Korc, M, RT-PCR analysis of laser-captured cells points to potential paracrine and autocrine actions on neurotrophins in pancreatic cancer. submitted(2005), submitted.
Sensi, S; Yin, H; Carriedo, S; Rao, S; Weiss, J, Preferential Zn2+ influx through Ca2+- permeable AMPA/ kainate channels triggers prolonged mitochondrial superoxide production. Proceedings of the National Academy of Sciences(1999), Mar 2;96(5):2414-9.
Rao, S; Yin, HZ; Weiss, JH, Disruption of Astrocytic Glutamate Transport by Reactive Oxygen Species Produced in Motor Neurons in Response to Excitotoxic Activation: An In Vitro Model of ALS Pathogenesis. Annual Meeting of the American Academy of Neurology(2003), .
Rao, S; Weiss, JH. , Glutamate induces selective reactive oxygen species (ROS) generation in cultured motor neurons. Society for Neuroscience Abstracts(2001), .
Sensi, SL; Yin HZ; Amindari, S; Aminirati, G; Rao, S; Weiss, JH., Mitochondrial uptake of cytosolic Zn2+ in cortical neurons. Society for Neuroscience Abstracts(2000), .
Rao, S; Carriedo, S; Nguyen J; Weiss, J, Selective vulnerability of motor neurons to AMPA/kainate receptor mediated injury and mutant Cu/Zn superoxide dismutase. Society for Neuroscience Abstracts(1999), .
